DSM Biologics, a unit of DSM Pharmaceutical Products, is a provider of manufacturing technology and services to the biopharmaceutical industry. In addition to offering manufacturing services, DSM Biologics has co-exclusive rights, along with Dutch biotech company Crucell N.V., to license the high-producing PER.C6 human cell line as a production platform for recombinant proteins and monoclonal antibodies. DSM Biologics’ FDA-approved facility in Groningen, Netherlands was established in 1986 and has a strong track record for using a range of cell lines (PER.C6, CHO, hybridoma, etc.) in biopharmaceutical manufacturing. In addition, this site has a range of experience using multiple manufacturing (batch, fed-batch and continuous perfusion) and purification techniques.
The combination of the PER.C6 human cell line with DSM’s manufacturing services provides companies with a turn-key biologic manufacturing solution that reduces cost, risk and time to market.
Capabilities:
- PER.C6 manufacturing platform
- Preclinical, clinical and cGMP commercial manufacturing
- Batch, fed-batch and continuous perfusion
- Process development, optimization and scale up
- Downstream processing
- Process validation
- Purification chromatography
- Analytical development
- Fill and finish services
